Fish Oil Omega-3 Fatty Acid Research

Scientific research supporting the claim that Omega-3 Fatty Acids help Support a Healthy Heart. Fish Oil Home Rissanen, T. S. Voutilainen, K. Myyssonen, T.A. Lakka, and J. T. Salonen. "Fish oil-derived fatty acids, dodosahexaenoic acid, and docosapentaenoic acid, and the risk of acute coronary events: The Kuopio ischaemic heart disease risk factor study." Circulation 102:2677-2679 (2000). Singh, Ram B., et al. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival. Cardiovascular Drugs and Therapy 11:485-91 (1997). Von Schacky, C., P. Angerer, W. Kothny, K. Theisen, and H. Mudra. "The effect of dietary omega-3 fatty acids on coronary atherosclerosis: A randomized, double-blind placebo-controlled trial." Ann Intern Med 130:554-562 (1999). von Schacky, Clemens. n-3 fatty acids and the prevention of coronary atherosclerosis. American Journal of Clinical Nutrition 71(suppl):S224-27S (2000). Christensen, J. H., M. S. Christensen, J. Dyerberg, and E. B. Schmidt. "Heart rate variability and fatty acid content of blood cell membranes: A dose-response study with n-3 fatty acids." Am J Clin Nutr 70:331-337 (1999). Christensen, Jeppe Hagstrup, et al. “Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n-3 fatty acids. “ American Journal of Clinical Nutrition 70:331-37 (1999). Christensen, Jeppe Hagstrup, et al. “Effect of fish oil on heart rate variability in survivors of myocardial infarction. “ British Medical Journal 312:677-78 (1996). Albert, C. M., C. H. Hennekens, C.I. O'Donnel, U. A. Ajani, V. J. Carey, and W. C. Willett. "Fish consumption and risk of sudden cardiac death." JAMA 279:23-28 (1998). Angerer P., Kothny W., Stork S., von Schacky C. “Effect of dietary supplementation with omega-3 fatty acids on progression of atherosclerosis in carotid arteries.” Klinikum der Universitat Munchen, Institut und Poliklinik fur Arbeits- und Umweltmedizin-Innenstadt, Ziemssenstrasse 1, Germany. Appel, Lawrence J., et al. “Does supplementation of diet with "fish oil" reduce blood pressure?” Archives of Internal Medicine 153:1429-38 (1993). Christensen, Jeppe Hagstrup, et al. “Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n-3 fatty acids. “ American Journal of Clinical Nutrition 70:331-37 (1999). Dehmer, G. J., J. J. Popma, E. K. van den Berg, E. J. Eichorn, J. B. Prewitt, W. B. Campbell, L. Jennings, J. T. Willerson, and J. M. Schmitz. "reduction in the rate of early restenosis after coronary angioplasty by a diet supplemented with n-3 fatty acids." N Engl J Med 319:733-740 (1998). Engler M. M., Engler M. B., Pierson D. M., Molteni L. B., Molteni A. “Effects of docosahexaenoic acid on vascular pathology and reactivity in hypertension.” Laboratory of Cardiovascular Physiology, Department of Physiological Nursing, University of California, San Francisco, California 94143-0610, USA. Eritsland, J., H. Arnesen, K. Bronseth, N. B. Fjeld, and M. Abdelnoor. "Effect of dietary supplementation with n-3 fatty acids on coronary artery bypass graft patency." Am J Cardio 77:31-36 (1996). Eritsland, J., et al. "Long-term effects of n-3 polyunsaturated fatty acids on haemostatic variables and bleeding episodes in patients with coronary artery disease." Blood Coagulation and Fibrinolysis  6:17-22 (1995). Flaten, Hugo, et al. “Fish-oil concentrate: effects of variables related to cardiovascular disease.“ American Journal of Clinical Nutrition 52:300-06 (1990). Geelen A., Brouwer I. A., Zock P. L., Kors J. A., Swenne C. A., Katan M. B., Schouten E. G. “(N-3) fatty acids do not affect electrocardiographic characteristics of healthy men and women.  J Nutr 132(10):3051-4 (2002). GISSI-Prevenzione Investigators. "Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-Prevenzione trial." Lancet 354:447-455 (1999). Harris, W. S., and W. L. Isley. "Clinical trial evidence for the cardioprotective effects of omega-3 fatty acids." Curr Atheroscler Rep 3:174-197 (2001). Leaf, A., G. E. Billman, and H. Hallaq. "Prevention of ischemia-induced ventricular fibrillation by omega-3 fatty acids." Proc Nat Acad Sci USA 91:4427-4430 (1994). Leaf, A., and J. X. Kang. "Dietary n-3 fatty acids in the prevention of lethal cardiac arrhythmias." Curr Opin Lipidol 8:4-6 (1997). Leaf, A., J. X. Kang, Y F. Xiao, and G. E. Billman. "Dietary n-3 fatty acids in the prevention of cardiac arrhythmias." Curr Opin Clin Nutr Metab Care 1:225-228 (1998). Marchioli, Roberto, et al. “Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction: results of GISSI-Prevenzione trial. “ Lipids 36:S119-S126 (2001). Marchioli, Roberto, et al. “Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of GISSI-Prevenzione. “ Circulation 105:1897-1903 (2002). Morris, Martha Clare, et al. “Does fish oil lower blood pressure? A meta-analysis of controlled trials.“ Circulation 88(2):523-33 (1993). Olszewski, A. J. "Fish oil decreases homocysteine in hyperlipidemic men." Coronary Artery Dis 4:53-60 (1993). Radack, K. C. Deck, and G. Huster. "Dietary supplementation with low-dose fish oils lowers fibrinogen levels." Ann Intern Med 11:757-758 (1989). Radack, Kenneth, et al. “The effects of low doses of n-3 fatty acid supplementation on blood pressure in hypertensive subjects. “ Archives of Internal Medicine 151:1173-80 (1991).